https://www.ceesdekker.net Secrets

2009, discovery of a fresh phenotype for microorganisms in slim nanofluidic slits; and initial detection of neighborhood protein constructions along DNA making use of sound-condition nanopores

Springer Character or its licensor holds unique rights to this article under a publishing agreement with the creator(s) or other rightsholder(s); creator self-archiving on the acknowledged manuscript Edition of this short article is exclusively governed by the conditions of these publishing arrangement and applicable law.

We are tests a brand new procedure for linking publications to authors. You can assist! If you detect any inaccuracies, make sure you

I'm able to hardly imagine how I, as a geneticist, would be able to learn essential physics, not to mention compete at the top. How did you go over it?

Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent structure in 2005. (nl)

SMC complexes can go Actual physical roadblocks larger than their ring measurement, indicating a nontopological mechanism for DNA loop extrusion

We use nanofabricated microfluidic buildings to sample spatial boundaries for micro organism and biomimetic vesicles with reconstituted protein networks and this assess the fundamental role of spatial confinement at the molecular and mobile amount. Our initiatives include things like the next:

Example (one) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in gray, the rim with the pore is highlighted in red, and also a 3D rendering in the movement from the DNA rod is exhibited.

‘Yes, I recognize people have been astonished at time. At the conclusion of the nineties, when I was in my forties, I had been Professor of Molecular Electronics and I have to admit that it experienced turn into a bit bored, I didn’t understand much any more. The sector went extra into the appliance facet, how you can combine nanotubes into Digital circuits.

There was one particular challenge while — we didn't notice any measurable electrical conduction from The one polymer molecules. We concluded that at The one-molecule amount, conducting polymers ended up basically not such great conductors, which was instead disappointing. We Therefore broadened our see to try to locate much more promising molecules.

An built-in microfluidic System for quantifying drug permeation across biomimetic vesicle membranes

‘That considerations the artificial mobile, as Portion of the Dutch BaSyC initiative. Craig Venter appeared top-down in People times and identified about five hundred genes which have been minimally needed for the performing cell. We want to glance bottom-up: how do we transfer from a several molecules to an entire biological technique?

Visualization of unstained DNA nanostructures with Innovative in-concentration transmission electron microscopy techniques

Good-point out nanopores have tested to generally be a shockingly functional probe for one-molecule Assessment of DNA. I'll explain a number of our modern results – especially DNA knots – and also our attempts to increase the capabilities of solid-point out nanopores even further more, during the course of solitary-protein detection, graphene nanopores, plasmonic nanopores, and DNA https://www.ceesdekker.net origami nanopores.